ea0016p369 | Growth factors | ECE2008
Attanasio Andrea
, Mo Daojun
, Chanson Philippe
, Ho Ken
, Woodmansee Whitney
, Kleinberg David
, Erfurth Eva Marie
Patients with adult onset GHD (AO-GHD) manifest features of the metabolic syndrome (MetS) (abdominal obesity, dyslipidemia and insulin resistance), a condition associated with increased risk of diabetes mellitus (DM).We assessed metabolic status before and after 2 years of GH treatment and the occurrence of de novo DM in 712 patients with AO-GHD from HypoCCS drawn from the US (32.2%) and Europe (67.8%). Patients were divided into four BMI categori...